I graduated with a bachelor’s degree in Biology from Eskişehir Osmangazi University in Turkey. Following my bachelor’s, I have attended master’s studies in Biotechnology at Adam Mickiewicz University in Poland and prepared my master’s thesis at the Institute of Human Genetics, Polish Academy of Sciences where I am currently a PhD student. As a PhD student, I am specializing in RNA-Sequencing and Mass Spectrometry data analysis and integration of transcriptome and proteome data to decipher mechanisms of post-transcriptional regulation of gene expression during development. My current research is focused on the role of NANOS post-transcriptional regulators during germ cell development and its connection to fertility by using molecular biology, bioinformatics and computational biology approaches.
mgr Erkut Ilaslan
Publications
Role of PUM RNA-Binding Proteins in Cancer.
Smialek M, Ilaslan E, Sajek M, Jaruzelska J
Cancers 2021, 13 (1), 129; https://doi.org/10.3390/cancers13010129IF-6,126 MNiSW-140
The FKBP4 gene, encoding a regulator of the androgen receptor signaling pathway, is a novel candidate gene for androgen insensitivity syndrome.
Ilaslan E, Markosyan R, Sproll P, Stevenson BJ, Sajek M, Sajek MP, Hayrapetyan H, Sarkisian T, Livshits L, Nef S, Jaruzelska J, Kusz-Zamelczyk K
Internatl J Molecular Sciences, 2020 Nov-1, e8403,11 str, doi:10.3390/ijms21218403IF-4,556 MNiSW-140
Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line.
Janecki DM, Ilaslan E, Śmiałek MJ, Sajek MP, Kotecki M, Ginter-Matuszewska B, Krainski P, Jaruzelska J, Kusz-Zamelczyk K
Int J Molec Sciences, 2020, 2 (8), 3009; 14 str., doi:10.3390/ijms21083009, Epub Apr 24IF-4,556 MNiSW-140
Characterization of RNP networks of PUM1 and PUM2 post-transcriptional regulators in TCam-2 cells, a human male germ cell model.
Śmiałek MJ, Ilaslan E, Sajek MP, Świercz A, Janecki DM, Kusz-Zamelczyk K, Woźniak T, Kotecki M, Handschuh L, Figlerowicz M, Jaruzelska J
Cells, 2020 Apr 16, 9 (4): 984, doi: 10.3390/cells9040984IF-4,366 MNiSW-140
Kinesin KIF18A is a novel PUM- regulated target promoting mitotic progression and survival of human male germ cell line.
Śmialek MJ, Kuczyńska B, Ilaslan E, Janecki DM, Sajek MP, Kusz-Zamelczyk K, Jaruzelska J
Journal of Cell Science, 2020, 133 jcs240986, 8 stron, doi: 10.1242/jcs.240986 Epub 2020 Mar 24IF-4,573 MNiSW-140
PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues.
Sajek M, Janecki DM, Śmiałek MJ, Ginter-Matuszewska B, Spik A, Oczkowski S, Ilaslan E, Kusz-Zamelczyk K, Kotecki M, Blazewicz J, Jaruzelska J;
Cell Mol Life Sci, 2019, 76 (1): 147-161.
A case of two sisters suffering from 46,XY gonadal dysgenesis and carrying a mutation of a novel candidate sex-determining gene STARD8 on the X chromosome
Ilaslan E, Calvel P, Nowak D, Szarras-Czapnik M, Slowikowska-Hilczer J, Spik A, Sararols P, Nef S, Jaruzelska J, Kusz-Zamelczyk K;
Sexual Dev, 2018, 12 (4): 191-195.
All publications
Awards
prof. dr hab. n. biol. Jadwiga Jaruzelska
dr n. med. Marcin Sajek
dr n. med. Maciej Śmiałek
mgr Erkut Ilaslan
Award of the Faculty of Medical Sciences of the Polish Academy of Sciences
Prof. Jadwiga Jaruzelska, dr Marcin Piotr Sajek, dr Maciej Jerzy Śmiałek and Ms Erkut Ilaslan were awarded by Medical Division of the Polish Academy of Sciences for 5 articles entitled: “Role of NANOS and PUM proteins in human reproduction and infertility”.
Scholarship
Scholarship 2020/21
dr n. med. Marcin Sajek
dr n. med. Maciej Śmiałek
mgr Erkut Ilaslan
dr hab. n. med. Kamila Kusz-Zamelczyk
prof. dr hab. n. biol. Jadwiga Jaruzelska
mgr inż. Damian Janecki
Publication of the year 2019
Award of the Director of the Institute of Human Genetics of the Polish Academy of Sciences for a review entitled „PUM1 and PUM2 exhibit different modes of regulation for SIAH1 That Involve cooperativity with Nanos paralogues" published in the journal Cellular and Molecular Life Sciences, which awarded the title PUBLICATION OF THE YEAR 2019.
