{"id":1331,"date":"2015-11-05T12:09:11","date_gmt":"2015-11-05T12:09:11","guid":{"rendered":"http:\/\/igcz.poznan.pl\/en\/zaklad-patologii-molekularnej\/"},"modified":"2026-04-07T07:49:51","modified_gmt":"2026-04-07T07:49:51","slug":"department-of-molecular-pathology","status":"publish","type":"page","link":"https:\/\/igcz.poznan.pl\/en\/structure\/department-of-molecular-pathology\/","title":{"rendered":"Department of Molecular Pathology"},"content":{"rendered":"

The Department of Molecular Pathology focuses on research on the molecular basis of human diseases, with particular emphasis on lifestyle diseases such as cancer and cardiovascular diseases. We are committed to developing innovative cell therapies, including those based on CAR-T technology. We have a wide portfolio of techniques allowing for the functional characterization of non-coding genome sequences in cellular processes and tumor pathogenesis. We use pluripotent cells (iPSC) to create advanced tissue models, such as Engineered Heart Tissue (EHT), used to study the interactions between cardiomyocytes and fibroblasts in the heart and develop new therapeutic approaches. We conduct research on cellular models both in traditional cultures and in 3D. Our preclinical studies are mainly based on the use of immunocompromised animal models enabling the evaluation of proposed therapeutic approaches in a xenogeneic system.<\/p>\n

There are two independent research groups within the Department:<\/p>\n

Independent Research Group of Non-coding Parts of the Genome<\/strong><\/a> led by prof. IHG PAS Ph.D. Agnieszka Dzikiewicz Krawczyk.<\/p>\n

Independent Research Group for Advanced Tissue Modelling<\/strong><\/a> led by prof. IHG PAS Ph.D. Tomasz Kolanowski.<\/p>\n","protected":false},"excerpt":{"rendered":"

The Department of Molecular Pathology focuses on research on the molecular basis of human diseases, with particular emphasis on lifestyle diseases such as cancer and cardiovascular diseases. We are committed to developing innovative cell therapies, including those based on CAR-T technology. We have a wide portfolio of techniques allowing for the functional characterization of non-coding […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1336,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/department.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1331","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nDepartment of Molecular Pathology - Institute of Human Genetics Polish Academy of Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/igcz.poznan.pl\/en\/structure\/department-of-molecular-pathology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Department of Molecular Pathology - Institute of Human Genetics Polish Academy of Sciences\" \/>\n<meta property=\"og:description\" content=\"The Department of Molecular Pathology focuses on research on the molecular basis of human diseases, with particular emphasis on lifestyle diseases such as cancer and cardiovascular diseases. 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