- Timetable of the lecture “Molecular basis of tumors” – winter semester 2025/2026
- SYLLABUS of the lecture “Molecular basis of tumors” – winter semester 2025/2026
Lecture
Molecular basis of tumors
winter semester 2025/2026
(This lecture is obligatory)
Lectures will be held in hybrid mode.
|
Data |
Topic (Solid tumors) |
|
08.10.2025 9:00 – 9:45 |
Introduction to carcinogenesis, (dr hab. Katarzyna Kiwerska) |
|
15.10.2025 9:00 – 10:30 |
Molecular alterations in solid tumors, |
|
22.10.2025 9:00 -9:45
|
Modern treatment of solid tumors, (prof. Małgorzata Wierzbicka) on-line |
|
29.10.2025 9:00 -10:30
|
microRNA in cancer genetics,(dr Paulina Gałka-Marciniak) |
|
05.11.2025 9:00 – 9:45 10:00 – 10:45 |
The importance of 3D in vitro and in vivo experimental models in understanding tumor biology and developing therapies, (dr hab. Iwona Ziółkowska-Suchanek) Spatial transcriptomics – bridging histopathology and genomics in cancer research, (dr Szymon Hryhorowicz) |
|
12.11.2025 11:00 – 11:45 |
Mutational signatures: from discovering the footprints of mutational processes to their clinical application, (prof. Reiner Siebert) on-line |
|
19.11.2025 9:00 – 10:30 |
Hereditary cancers, (dr hab. Bartłomiej Budny) |
|
26.11.2025 9:00 – 9:45 10:00 – 10:45 |
Molecular mechanism of drug resistance in cancer cells of solid tumors, (prof. Radosław Januchowski) Modern diagnostics of solid tumors, (dr Katarzyna Kiwerska) |
|
Data |
Topic (Hematologic neoplasms) |
|
03.12.2025 9:00 – 9:45 |
The molecular basis of hematological neoplasm – introduction, (dr hab. Małgorzata Dawidowska, prof. IGC) |
|
10.12.2025 9:00 – 9:45 |
The tumor microenvironment: an integral component of cancer (dr Arjan Diepstra) on-line |
|
17.12.2025 9:00 – 9:45 10:00 – 10:45 |
Epigenetics of hematologic neoplasms – Burkitt lymphoma, (dr hab. Agnieszka Dzikiewicz-Krawczyk, prof. IGC) Epigenetics of hematologic neoplasms – Hodgkin lymphoma, (dr Kinga Bednarek) |
|
07.01.2026 9:00 – 10:30 |
Modern diagnostics of hematologic neoplasms, (dr hab. Małgorzata Jarmuż-Szymczak, prof. IGC) |
|
14.01.2026 9:00 – 9:45 |
Molecular mechanism of drug resistance in cancer cells of hematologic neoplasms, (prof. Dominik Dytfeld) |
|
21.01.2026 9:00 -10:30 |
Modern treatment of hematologic neoplasms, (prof. Lidia Gil) |
SYLLABUS
Winter semester 2025/2026
| Course |
Molecular basis of tumors |
| Host Institution | Institute of Human GeneticsPolish Academy of SciencesStrzeszyńska Street, 32 |
| Language | English |
| The expected effects of teaching in terms of: knowledge, skills and social qualifications |
Ph. D. student is supposed to: 1.Gain knowledge in several aspects of cancer genetics and epigenetics, molecular diagnostics and therapy. In particular, the following specific topics will be elaborated: – molecular and chromosomal alterations in solid and hematologic neoplasms, viral carcinogenesis – field cancerization, the Califano model – the role of miRNA in cancer – the role of the tumor microenvironment – the process of detoxification and drug resistance in neoplastic cells – epigenetics of hematologic neoplasms – visualization strategies of alterations found in tumor cells – molecular diagnostics and treatment of cancer – models in cancer research – mutational signatures and their clinical relevance – characterization of differences between sporadic and hereditary cancer 2. Get familiar with new directions in the field of cancer genetics. 3. Learn how to formulate scientific questions in the field of cancer genetics. |
| Type of course | obligatory |
| Semester/year | winter semester 2025/2026 |
| First name/family name of the person responsible for the course | prof. IGC dr hab. Małgorzata Jarmuż-Szymczak |
| First name/family name of the person responsible for the exam | prof. IGC dr hab. Małgorzata Jarmuż-Szymczak |
| Format | Lecture will be held in English with usage of audio-visual equipment. |
| Basic and additional requirements | Skills in English and knowledge in molecular biology and mathematics |
| Number of ECTSs | 3 ECTS |
| ECTSs summary | 1 ECTS corresponds to 25-30 hours of personal studies focused on broadening knowledge based on suggested bibliography (vide bibliography list below). |
| Method of teaching | Lectures will be held using power point presentation and a multimedia projector |
| Method of evaluation | written exam in form of a test |
| Prerequisite for passing | Positive score at the exam |
| Topics |
– molecular and chromosomal alterations in solid and hematologic neoplasms – field cancerization, the Califano model, viral carcinogenesis – the role of miRNA in cancer – the role of the tumor microenvironment – the process of detoxification and drug resistance in neoplastic cells – epigenetics of hematologic neoplasms – visualization strategies of alterations found in tumor cells – molecular diagnostics and treatment of cancer – models in cancer research – mutational signatures and their clinical relevance – characterization of differences between sporadic and hereditary cancer |
| Additional material | Presentation of each lecture in PDF format |
| Bibliography | Will be suggested later |