Our scientific interests concentrate on cancer genetics and the genetics of the senses. We use various techniques in our routine practice, from molecular biology and cytogenetics (microarrays, NGS, pyrosequencing, FISH and FICTION) supplemented by functional analyses. The aim of the research is the identification of genomic and epigenomic alterations that contribute to the development of neoplasms and diseases of the sensory organs. To that end, we work closely with renowned Polish and foreign scientific groups.

Keywords:

Featured publications

Transcriptional reprogramming by mutated IRF4 in lymphoma.

Schleussner N, Cauchy P, Franke V, Giefing M, Fornes O, Vankadari N, Assi SA, Costanza M, Weniger MA, Akalin A, Anagnostopoulos I, Bukur T, Casarotto MG, Damm F, Daumke O, Edginton-White B, Gebhardt JCM, Grau M, Grunwald S, Hansmann ML, Hartmann S, Huber L, Kärgel E, Lusatis S, Noerenberg D, Obier N, Pannicke U, Fischer A, Reisser A, Rosenwald A, Schwarz K, Sundararaj S, Weilemann A, Winkler W, Xu W, Lenz G, Rajewsky K, Wasserman WW, Cockerill PN, Scheidereit C, Siebert R, Küppers R, Grosschedl R, Janz M, Bonifer C, Mathas S

Nature Commun, 2023 Nov 7; 14 (1): 6 947. doi: 10.1038/s41467-023-41954-8.

IF-16.6 MNiSW-200

Featured research projects

1. Project OPUS

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„Genome-wide mutation screen of the regulome in laryngeal squamous cell carcinoma.”

Duration: 2017-2020

2. Project PRELUDIUM

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„Role of miR-299-5p in pathogenesis of laryngeal squamous cell carcinoma.”

Duration: 2017-2020

3. Project OPUS

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“The expression analysis of genes and proteins potentially involved in lymph node metastasis formation in laryngeal cancer”

Duration: 2016-2019

4. Project HARMONIA

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“Identification of miRNAs involved in classical Hodgkin lymphoma pathogenesis using combined expression and mutation profiling and functional analyses.”

Duration: 2015-2018

5. Project HARMONIA

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“Whole exome sequencing in Polish patients with sporadic keratoconus and a pilot study of keratoconus proteomic and metabolomic profiles of tears.”

Duration: 2014-2017

6. Project PRELUDIUM

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“Silencing and functional analysis of the CDK1 gene in laryngeal squamous cell carcinoma.”

Duration: 2014-2017

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Collaborations

Awards

Awarded:
Given by:

Awarded: dr n. med. i n. o zdr. Joanna Świerkowska
Nagroda Polskiego Towarzystwa Genetyki Człowieka za najlepszą pracę doktorską z zakresu genetyki człowieka
Given by: Polskie Towarzystwo Genetyki Człowieka (PTGC)

Podczas XI Zjazdu Polskiego Towarzystwa Genetyki Człowieka w Bydgoszczy, dr n. med. i n. o zdr. Joanna Świerkowska otrzymała Nagrodę Polskiego Towarzystwa Genetyki Człowieka za najlepszą pracę doktorską z zakresu genetyki człowieka – stopień doktora nadany w latach 2018-2020. Tytuł nagrodzonej pracy doktorskiej: „Charakterystyka wybranych aspektów (epi)–genetycznych w wysokiej krótkowzroczności u polskich pacjentów”.

Awarded: mgr inż. Ewelina Kowal-Wiśniewska
Nagroda im. prof. Aleksandra Szczygła za pracę naukowo-badawczą opublikowaną w roku 2021
Given by: Polskie Towarzystwo Nauk Żywieniowych

za pracę naukowo-badawczą opublikowaną w roku 2021 z zakresu nauki o żywieniu człowieka: Alteration of the Early Development Environment by Maternal Diet and the Occurrence of Autistic-like Phenotypes in Rat Offspring.

Awarded: dr n. med. Julia Paczkowska
IX Edition of the Competition of the Polish Academy of Sciences in Poznan for the best scientific publication, which was published in 2020 and the lead author was a PhD student.
Given by: Polish Academy of Sciences in Poznan

Dr Julia Paczkowska – lauerate of the IX Edition of the Competition of the Polish Academy of Sciences in Poznan for the best scientific publication, which was published in 2020 and the lead author was a PhD student.

Awarded:
prof. dr hab. n. med. i n. o zdr. Maciej Giefing
dr hab. n. med. Małgorzata Jarmuż-Szymczak
dr hab. n. med. i n. o zdr. Katarzyna Kiwerska
dr n. med. Magdalena Kostrzewska-Poczekaj
Award of the Division of Medical Sciences of the Polish Academy of Sciences
Given by: Division of Medical Sciences of the Polish Academy of Sciences

for 5 publications concerning loss of tumor suppressor genes in squamous cell carcinoma

Awarded: dr n. med. i n. o zdr. Joanna Świerkowska
EMBO Short-term fellowship
Given by: EMBO

Joanna Świerkowska from the Department of Cancer Genetics received an EMBO short-term fellowship for the implementation of the project “The role of the noncoding miRNA and enhancers in high myopia” at Erasmus Medical Center, Rotterdam, The Netherlands

Awarded: dr n. med. Magdalena Kostrzewska-Poczekaj
EMBO short-term fellowship
Given by: EMBO

Magdalena Kostrzewska-Poczekaj from the Department of Cancer Genetics received an EMBO short-term fellowship for the implementation of the project "Platelets and platelet microparticles (PMP) as omnipresent RNA messengers in inflammatory diseases" at University Hospital Schleswig Holstein, Clinic for Otorhinolaryngology - Head and Neck Surgery, Luebeck in Germany.

Awarded: prof. dr hab. n. med. i n. o zdr. Maciej Giefing
Powołanie na członka Rady Naukowej Instytutu Genetyki Człowieka PAN w Poznaniu na kadencję 2019-2022.
Given by: Rada Naukowa Instytutu Genetyki Człowieka PAN

Awarded: prof. dr hab. n. med. Marzena Gajęcka
Kosciuszko Foundation Fellowship
Given by: Kosciuszko Foundation

Prof. Marzena Gajecka has been awarded a Kosciuszko Foundation Fellowship for the academic year 2019/2020, to visit Baylor College of Medicine and Texas Children’s Hospital in Houston, TX, US. The Kosciuszko Foundation promotes closer ties between Poland and the United States through educational, scientific and cultural exchanges. The Kosciuszko Foundation annually awards a number of Fellowships/Grants to Poles for advanced study, research, and/or teaching at universities and other institutions of higher learning in the United States.

Awarded: mgr Adam Ustaszewski
Msc Adam Ustaszewski otrzymał stypendium międzynarodowe (Short-Term Fellowship) przyznane przez Europejską Organizację Biologii Molekularnej (EMBO)
Given by: European Molecular Biology Organization (EMBO).

Mgr Adam Ustaszewski otrzymał stypendium międzynarodowe (Short-Term Fellowship) przyznane przez Europejską Organizację Biologii Molekularnej (EMBO) na projekt badawczy zatytułowany „Identification of putative alternations of open chromatin regions in Classical Hodgkin Lymphoma by integration of ATAC-Seq and high-throughput sequencing of cis-regulatory elements.”, przyznane przez Europejską Organizację Biologii Molekularnej (EMBO). Poznań. 24.01.2019 r.