I graduated Biotechnology at the Poznan University of Life Science and Dietetics and Nutrition at the Poznan University of Medical Sciences. My research interests in the Department of Cancer Genetics PAS are involved in genome of Head and Neck Squamous Cell Carcinoma. In my work, I focus mainly on searching for the novel LSCC oncogenes. Recently (XII.2019-II.2020) I have been a participant of European Molecular Biology Organisation in Department of Otorhinolaryngology, University Hospital of Schleswig‐Holstein in Lübeck (Germany).
dr n. med. Magdalena Kostrzewska-Poczekaj
Publications
Long read sequencing identifies complex structural variant landscape and recurrent TERT rearrangements in mucoepidermoid carcinoma.
Gensterblum-Miller E, Bhangale A, Majid D Al, Pienkowski VM, Rydzanicz M, Janiszewska J, Kostrzewska-Poczekaj M, Chang C, Brummel C, Michmerhuizen NL,Wang J, Sandford E, Tewari M, Wierzbicka M, Birkeland AC, McHugh JB, Spector ME, Giefing M, Jarmuz-Szymczak M, Heft Neal ME, Brenner JC
Oral Oncology, 2024, Volume 159, doi: 10.1016/j.oraloncology.2024.107108IF-4.0 MNiSW-140
TYK2 protein expression and its potential as the tissue-based biomarker for the diagnosis of colorectal cancer.
Zadka Ł, Ustaszewski A, Glatzel-Plucińska N, Rusak A,, Łaczmańska I, Ratajczak-Wielgomas K, Kmiecik A, Piotrowska A, Haczkiewicz-Leśniak K, Gomułkiewicz A, Kostrzewska-Poczekaj M, Dzięgiel P
Cancers (MDPI) 2024 Oct 30, 16 (21(: 3665, 23 str., doi.org/10.3390/cancers16213665IF-4.5 MNiSW-140
Bortezomib- and carfilzomib-resistant myeloma cells show increased activity of all three arms of the unfolded protein response.
Kubicki T, Bednarek K, Kostrzewska-Poczekaj M, Luczak M, Lewandowski K, Gil L, Jarmuż-Szymczak M, Dytfeld D
Am J Cancer Res, 2022;12 (7):3280-3293 www.ajcr.us /ISSN:2156-6976/ajcr0143092IF-5,942 MNiSW-100
Laryngeal squamous cell carcinoma cell lines show high tolerance for siRNA-mediated CDK1 knockdown.
Bednarek K, Kostrzewska-Poczekaj M, Ustaszewski A, Janiszewska J, Kiwerska K, Paczkowska J, Grenman R, Giefing M, Jarmuż-Szymczak M.
Amer J Cancer Res, 2021, 11 (5): 2081-2094IF-5,177 MNiSW-100
Assessing various control samples for microarray gene expression profiling of head and neck squamous cell carcinoma.
Ustaszewski A; Kostrzewska-Poczekaj M, Janiszewska J, Jarmuż-Szymczak M, Wierzbicka M; Marszal J, Grenman R, Giefing M
Biomolecules, 2021,11, e588. 9 stron, https://doi.org/10.3390/biom11040588IF-4,082 MNiSW-100
Copy number gains of the putative CRKL oncogene in laryngeal squamous cell carcinoma result in strong nuclear expression of the protein and influence cell proliferation and migration.
Kostrzewska-Poczekaj M, Bednarek K, Jarmuż-Szymczak M, Bodnar M, Filas V, Marszałek A, Bartochowska A, Grenman R, Kiwerska K, Szyfter K, Giefing M;
Sci Rep., 2020, 10, art.: 24 9 str., https://doi.org/10.1038/s41598-019-56870-5IF-3,998 MNiSW-140
DIAPH2 alterations increase cellular motility and may contribute to the metastatic potential of laryngeal squamous carcinoma.
Kostrzewska-Poczekaj M, Byzia E, Soloch N, Jarmuż-Szymczak M, Janiszewska J, Kowal E, Paczkowska J, Kiwerska K, Wierzbicka M, Bartochowska A, Ustaszewski A, Greczka G, Grenman R, Szyfter K, Giefing M;
Carcinogenesis, 2019, 40 (10): 1251-1259, Epub Feb 21, doi: 10.1093/carcin/bgz035
Downregulation of CEACAM6 gene expression in laryngeal squamous cell carcinoma is an effect of DNA hypermethylation and correlates with disease progression.
Bednarek K, Kostrzewska-Poczekaj M, Szaumkessel M, Kiwerska K, Paczkowska J, Byzia E, Ustaszewski A, Janiszewska J, Bartochowska A, Grenmann R, Wierzbicka M, Szyfter K, Giefing M, Jarmuż-Szymczak M;
Am J Cancer Res, 2018, 8 (7): 1249-1261.
Recurrent transcriptional loss of the PCDH17 tumor suppressor in laryngeal squamous cell carcinoma is partially mediated by aberrant promoter DNA methylation.
Byzia E, Soloch N, Bodnar M, Szaumkessel M, Kiwereska K, Kostrzewska-Poczekaj M, Jarmuż-Szymczak M, Szylberg L, Wierzbicka M, Bartochowska A, Kalinowicz E, Grenman R, Szyfter K, Marszalek A, Giefing M;
Molecular Carcinogenesis, 2018, 57 (7): 878-885.
Autosomal recessive cone-rod dystrophy can be caused by mutations in the ATF6 gene.
26. Skorczyk-Werner A, Chiang W-Ch, Wawrocka A, Wicher K, Jarmuż-Szymczak M, Kostrzewska-Poczekaj M, Jamsheer A, Ploski R, Rydzanicz M, Pojda-Wilczek D, Weisschuh N, Wissinger B, Kohl S, Lin JH, Krawczynski MR<
Eur J Human Genetics, 2017, 25 (11): 1210-1216.
All publications
Events
3-6.09.2014 Where:
Bydgoszcz
VI Congress of Contemporary Oncology -Next Generation
18-21.04.2012 Where:
Poznan
5th European Conference on Head and Neck Oncology
3-6 June 2010 Where:
Nijmegen, The Netherlands
12th European Workshop on Cytogenetics and Molecular Genetics of Solid Tumors
9-12 June 2010 Where:
Warsaw
XLIV Congress of Polish Society of Otorhinolaryngologists Head and Neck Surgeons, IV Congress of Polish Society of Skull Base Surgeons
19-21.11.2008 Where:
Poznan
IX National Scientific Conference - Tobacco and Health "Smoke is Poison"
4-8.06.2008 Where:
Lodz
43 - Congress of the Polish Society of Otolaryngologists, Head and Neck Surgeons
Awards
Awarded:
prof. dr hab. n. med. i n. o zdr. Maciej Giefing
dr hab. n. med. Małgorzata Jarmuż-Szymczak
dr hab. n. med. i n. o zdr. Katarzyna Kiwerska
dr n. med. Magdalena Kostrzewska-Poczekaj
prof. dr hab. n. med. i n. o zdr. Maciej Giefing
dr hab. n. med. Małgorzata Jarmuż-Szymczak
dr hab. n. med. i n. o zdr. Katarzyna Kiwerska
dr n. med. Magdalena Kostrzewska-Poczekaj
Award of the Division of Medical Sciences of the Polish Academy of Sciences
Given by: Division of Medical Sciences of the Polish Academy of Sciences
for 5 publications concerning loss of tumor suppressor genes in squamous cell carcinoma
Awarded:
dr n. med. Magdalena Kostrzewska-Poczekaj
EMBO short-term fellowship
Given by: EMBO
Magdalena Kostrzewska-Poczekaj from the Department of Cancer Genetics received an EMBO short-term fellowship for the implementation of the project "Platelets and platelet microparticles (PMP) as omnipresent RNA messengers in inflammatory diseases" at University Hospital Schleswig Holstein, Clinic for Otorhinolaryngology - Head and Neck Surgery, Luebeck in Germany.
Awarded:
dr n. farm. Justyna Karolak
dr n. med. Magdalena Kostrzewska-Poczekaj
dr n. farm. Justyna Karolak
dr n. med. Magdalena Kostrzewska-Poczekaj
Scholarship
Given by: Regional Labour Office
“Scholarship for PhD students specializing in strategic fields for Wielkopolska’s development”
Awarded:
dr n. med. Kinga Bednarek
dr n. med. Magdalena Kostrzewska-Poczekaj
dr n. med. Marcin Szaumkessel
prof. dr hab. n. med. i n. o zdr. Maciej Giefing
prof. dr hab. n. med. Krzysztof Szyfter
dr hab. n. med. Małgorzata Jarmuż-Szymczak
dr n. med. Kinga Bednarek
dr n. med. Magdalena Kostrzewska-Poczekaj
dr n. med. Marcin Szaumkessel
prof. dr hab. n. med. i n. o zdr. Maciej Giefing
prof. dr hab. n. med. Krzysztof Szyfter
dr hab. n. med. Małgorzata Jarmuż-Szymczak
„Golden Helix”
Given by: Scientific committee of the IV Polish Congress of Genetics in the Oncogenetics section
Poster price „CDK1 – new oncogene in squamous cell carcinoma of the larynx?”
Awarded:
dr n. med. Magdalena Kostrzewska-Poczekaj
III miejsce Best Poster Presentation Contest
Given by: Gliwice Scientific Meetings
“Analysis of CDK1 gene expression in squamous cell carcinoma of larynx”, 15-16.11.2013
Awarded:
dr n. med. i n. o zdr. Joanna Janiszewska
dr n. med. Marcin Szaumkessel
prof. dr hab. n. med. i n. o zdr. Maciej Giefing
dr hab. n. med. Małgorzata Jarmuż-Szymczak
dr n. med. Magdalena Kostrzewska-Poczekaj
prof. dr hab. n. med. Krzysztof Szyfter
dr n. med. i n. o zdr. Joanna Janiszewska
dr n. med. Marcin Szaumkessel
prof. dr hab. n. med. i n. o zdr. Maciej Giefing
dr hab. n. med. Małgorzata Jarmuż-Szymczak
dr n. med. Magdalena Kostrzewska-Poczekaj
prof. dr hab. n. med. Krzysztof Szyfter
Poster price
Given by: Scientific committee of the V Congress of Contemporary Oncology
Poster price „Search for novel tumor suppressor genes regulated by potentially oncogenic microRNA”
Awarded:
dr n. med. Magdalena Kostrzewska-Poczekaj
1st place Best Poster Presentation
Given by: Congress of Genetics
Best Poster Presentation, 12-15. 09.2010
Awarded:
dr n. med. Magdalena Kostrzewska-Poczekaj
Young Investigator Grants
Given by: DNA Repair Workshop
5th DNA Repair Workshop, Smolenice 25-29 .05.2008.
