I am a graduate of Master Degree in Biotechnology at Poznań University of Life Sciences. Since October 2016 I am a PhD student in Department of Molecular and Clinical Genetics. My research is focused on analysis of miRNA expression profile in childhood T-cell acute lymphoblastic leukemia (T-ALL) and functional studies of influence of inhibition and mimicry of chosen miRNA on leukemia cells cultures.
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
Publications
Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T-ALL: focus on miR-363-3p and promoter methylation
Drobna-Śledzińska M, Maćkowska-Maślak N, Jaksik R, Kosmalska M, Szarzyńska B, Lejman M, Sędek Ł, Szczepański T, Taghon T, Van Vlierberghe P, Witt M, Dawidowska
M.
Genes Chromosomes Cancer, 2022 Dec, 61 (12): 720-733, doi: 10.1002/gcc.23085. Epub Jul 2IF-4,263 MNiSW-140
Small RNA-Seq Reveals Similar miRNA Transcriptome in Children and Young Adults with T-ALL and Indicates miR-143-3p as Novel Candidate Tumor Suppressor in This Leukemia
Dawidowska M, Maćkowska-Maślak N, Drobna-Śledzińska M, Kosmalska M, Jaksik R, Szymczak D, Jarmuż-Szymczak M, Sadowska-Klasa A, Wojtaszewska M, Sędek Ł, Wróbel T, Zaucha J.M, Szczepański T, Lewandowski K, Giebel S, Witt M
IF-6,208 MNiSW-140
CRISPRi for specific and miRNAs with high sequence homology.
Drobna-Śledzińska M, Maćkowska-Maślak N, Jaksik R, Dąbek P, Witt M, Dawidowska M
Scientific Reports, 2022, 12: 6237, doi: 10.1038/s41598-022-10336-3IF-4,380 MNiSW-140
RNA-seq library preparation for comprehensive transcriptome analysis in cancer cells.
Jaksik R, Drobna-Śledzińska M and Dawidowska M
Genomics, 2021 Nov, 11 (6): 4149-62, Epub Nov 3, doi.10.1016/j.ygeno.2021.10.018IF-5,736 MNiSW-100
DNA Methylation in T-Cell Acute Lymphoblastic Leukemia: In Search for Clinical and Biological Meaning.
Maćkowska N, Drobna-Śledzńska M, Witt M and Dawidowska M
Int J Mol Sci, Special Issue "Epigenetic Mechanisms and Human Pathology (MDPI), 2021, e1388, https://doi.org/10.3390/ijms22031388IF-4,556 MNiSW-140
hsa-miR-20b-5p and has-miR-363-3p affect expression of PTEN and BIM tumor suppressor genes and modulate survival of T-ALL Cells in vitro
Drobna M, Szarzyńska B, Jaksik P, Sędek Ł, Kuchmiy A, Taghon T, Van Vlierberghe P, Szczepański T, Witt M and Dawidowska M
Cells, 2020 May 5, 9 (5), 1137; doi:10.3390/cells9051137, 20 str,IF-4,366 MNiSW-140
Comprehensive investigation of miRNome identifies novel candidate miRNA-mRNA interactions implicated in T-cell acute lymphoblastic leukemia.
Dawidowska M, Jaksik R, Drobna M, Szarzyńska-Zawadzka B, Kosmalska M, Sędek Ł, Machowska L, Lalik A, Lejman M, Ussowicz M, Kałwak K, Kowalczyk JR, Szczepański T, Witt M;
Neoplasia, 2019, 21 (3): 294-310.
T-cell acute lymphoblastic leukemia from miRNA perspective: Basic concepts, experimental approaches, and potential biomarkers.
Drobna M, Szarzyńska-Zawadzka B, Dawidowska M;
Blood Reviews, 2018, 32 (6): 457-0472, Epub 2018 April 12.
Identification of endogenous control miRNAs for RT-qPCR in T-cell acute lymphoblastic leukemia.
Drobna M, Szarzyńska-Zawadzka B, Daca-Roszak P, Kosmalska M, Jaksis R, Witt M, Dawidowska M;
Int J Mol Sci, 2018, 19 (10): e2858 (17 stron); https://doi.org/10.3390/ijms19102858).
ZnO@ Gd2O3 core/shell nanoparticles for biomedical applications: Physicochemical, in vitro and in vivo characterization.
Woźniak A, Grześkowiak BF, Babayevska N, Zalewski T, Drobna M, Woźniak-Budych M, Wiweger M, Słomski R, Jurga S;
Materials Science and Engineering C, 2017, 80, 603-615.
All publications
Awards
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
2 Nagrodę w Specjalności Genetyka człowieka.
Given by: ZG PTG
W ramach II edycji konkursu organizowanego przez Polskie Towarzystwo Genetyczne na najlepszą pracę oryginalną oraz rozprawę doktorską w zakresie genetyki z 2023 roku
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
START is a scholarship programme for the best young researchers representing all fields of science. Grant can be used for any purpose, is intended to provide financial support to researchers at early stage of their research career and to enable them implementation of research plans.
START is a scholarship programme for the best young researchers representing all fields of science. Grant can be used for any purpose, is intended to provide financial support to researchers at early stage of their research career and to enable them implementation of research plans.
Given by: Foundationf for Polish Science START
For the 31st time, the Foundation for Polish Science awarded START scholarships to the most talented young scientists from all over Poland. This year, 100 young researchers will receive it, including Monika Drobna-Śledzińska, PhD student from the Department of Molecular and Clinical Genetics.
START is a scholarship programme for the best young researchers representing all fields of science. Grant can be used for any purpose, is intended to provide financial support to researchers at early stage of their research career and to enable them implementation of research plans.
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
Scholarship
Given by: Director IBCH PAS
Scholarship 2020/21
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
Scholarship from the City of Poznań for young researchers
Given by: Scholarship of City of Poznań
Monika Drobna, MSc. – PhD student from the Department of Molecular and Clinical Genetics has received a scholarship from the City of Poznań for young researchers for outstanding scientific activity and scientific achievements in the field of molecular research including microRNA, which are the basis of childhood T-cell acute lymphoblastic leukemia.
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
Honorable mention
Given by: Poznań branch of the Polish Academy of Sciences
Monika Drobna, MSc, was granted a honorable mention in the contest for the best original paper published in 2018, with a PhD student as the leading author, organized by the Poznań branch of the Polish Academy of Sciences. The work entitled „Identification of endogenous control miRNAs for RT-qPCR in T-cell acute lymphoblastic leukemia” [Drobna M, Szarzyńska-Zawadzka B, Daca-Roszak P, Kosmalska M, Jaksis R, Witt M, Dawidowska M; Int J Mol Sci, 2018, 19 (10): e2858].
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
Award for the best review publication in 2018
Given by: Director of the Institute of Human Genetics PAS
the best review publication in 2018 entitled: "T-cell acute lymphoblastic leukemia from miRNA perspective" published in the prestigious journal Blood Reviews
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
Stypendia dla Najlepszych Doktorantów na rok akademicki 2018/2019,
Given by: Środowiskowe Studium Doktoranckie Instytutu Chemii Bioorganicznej PAN
Awarded:
dr n. med. i n. o zdr. Monika Drobna-Śledzińska
Award in “City of Poznań Award for outstanding master thesis” contest for a thesis entitled “In vitro evaluation of the biofunctionalized nanoparticles’ effectiveness”.
Given by: Award in “City of Poznań Award for outstanding master thesis”.
Poznań 10 April 2017
